Thermo Fisher Scientific TAS2R16 Polyclonal Antibody
TAS2R16 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 IHC에 사용 가능. 인간 시료에 반응하며, 동결건조 형태로 제공. 단기 4°C, 장기 -20°C 보관 권장. 연구용으로만 사용.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:300–1:2,000 | - |
| Immunohistochemistry (IHC) | 1:300–1:2,000 | - |
| Miscellaneous PubMed (Misc) | - | View 2 publications |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from amino acid region 200–250 of human TAS2R16 conjugated to blue carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water.
- Centrifuge to remove any insoluble material.
- Specificity: TAS2R16.
Target Information
This gene encodes a member of a family of candidate taste receptors that belong to the G protein-coupled receptor superfamily. These receptors are expressed by taste receptor cells of the tongue and palate epithelia. Each gene encodes a 7-transmembrane receptor protein functioning as a bitter taste receptor.
The TAS2R16 gene is clustered with other taste receptor genes on chromosome 7 and is genetically linked to loci influencing bitter perception. It is a gustducin-coupled receptor involved in the perception of bitter compounds in the oral cavity and gastrointestinal tract, signaling through PLCB2 and the calcium-regulated cation channel TRPM5.
It is expressed in a subset of gustducin-positive taste receptor cells of the tongue. The Lys-172 polymorphism in TAS2R16 is associated with genetic susceptibility to alcoholism and confers bitter perception of salicin to non-taster mice.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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