Thermo Fisher Scientific COIL Monoclonal Antibody (4B8)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

ELISA (ELISA)

10 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Mouse / IgM, kappa

Class

Monoclonal

Type

Antibody

Clone

4B8

Immunogen

COIL (NP_004636, 477 a.a. approximately 575 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Coilin,uniProtId:P38432-1,ncbiNodeId:9606,antigenRange:477-575,antigenLength:576,antigenImageFileName:H00008161-M05A_Coilin_P38432-1_House_mouse.svg,antigenImageFileNamePDP:H00008161-M05A_Coilin_P38432-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Storage buffer

ascites

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: IAFKLLELTS SYSPDVSDYK EGRILSHNPE TQQVDIEILS SLPALREPGK FDLVYHNENG AEVVEYAVTQ ESKITVFWKE LIDPRLIIES PSNTSSTEP

Target Information

The protein encoded by this gene is an integral component of Cajal bodies (also called coiled bodies). Cajal bodies are nuclear suborganelles of varying number and composition that are involved in the post-transcriptional modification of small nuclear and small nucleolar RNAs. The N-terminus of the coilin protein directs its self-oligomerization while the C-terminus influences the number of nuclear bodies assembled per cell. Differential methylation and phosphorylation of coilin likely influences its localization among nuclear bodies and the composition and assembly of Cajal bodies. This gene has pseudogenes on chromosome 4 and chromosome 14.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.