Thermo Fisher Scientific MAGE1 Polyclonal Antibody
Thermo Fisher Scientific의 MAGE1 Polyclonal Antibody는 인간 MAGE-1 단백질을 인식하는 토끼 유래 IgG 항체로, 다양한 암 조직에서 발현 연구에 적합합니다. IHC(P) 실험에 사용 가능하며, 고농도(1 mg/mL) 액상 형태로 제공됩니다. 연구용으로만 사용됩니다.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 280–320 of Human MAGE-1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2802965 |
Target Information
Human malignant neoplasms carry rejection antigens recognized by autologous, tumor-directed, and specific cytolytic CD8+ T lymphocyte clones (CTL).
An important group of antigens is coded by the MAGE family of genes, identified as melanoma-associated antigens (MAAs).
MAGE-1 is expressed in a significant proportion of human neoplasms of various histological types — including melanoma, brain tumors of glial origin, neuroblastoma, non-small cell lung cancer, breast, gastric, colorectal, ovarian, and renal cell carcinomas — but not in normal tissues.
Therefore, the encoded antigen may serve as a marker for early detection and as a potential target for cancer immunotherapy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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