Thermo Fisher Scientific DEFA4 Polyclonal Antibody
DEFA4 단백질을 인식하는 Rabbit Polyclonal 항체로, Human, Mouse, Rat 시료에 반응합니다. IHC(P)에서 1:50–1:200 희석으로 사용 가능하며, 항원 친화 크로마토그래피로 정제되었습니다. PBS/glycerol buffer에 보관되며 연구용으로 적합합니다.
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- PA575435
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to the N-terminus of Human Defensin alpha4 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2719163 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen. The purity is greater than 95% (by SDS-PAGE).
Target Information
Defensins are a family of antimicrobial and cytotoxic peptides involved in host defense. They are abundant in neutrophil granules and present in epithelial tissues of mucosal surfaces such as intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family share high sequence similarity and a conserved cysteine motif. Several alpha defensin genes are clustered on chromosome 8. The DEFA4 gene differs by an extra 83-base segment, likely from a recent duplication within the coding region. The encoded protein, defensin alpha 4, is found in neutrophils and exhibits corticostatic activity by inhibiting corticotropin-stimulated corticosterone production.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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