Thermo Fisher Scientific Phospho-Cdc25A (Ser75) Polyclonal Antibody
인간, 마우스, 랫트 반응성의 Rabbit Polyclonal 항체로 Ser75 인산화된 Cdc25A를 인식합니다. Western blot, IHC, ELISA에 적합하며 항원 친화 크로마토그래피로 정제되었습니다. 액상 형태로 -20°C 보관, 연구용 전용 제품입니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (IHC) | 1:100–1:300 |
| ELISA | 1:5,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from human Cdc25A around the phosphorylation site of Ser75 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS (pH 7.4), with 50% glycerol, 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2609006 |
Product Specific Information
This antibody is predicted to react with mouse and rat based on sequence homology.
Target Information
CDC25A is a member of the CDC25 family of phosphatases. Three CDC25 genes (CDC25A, CDC25B, CDC25C) are present in human cells and function at different phases of the cell cycle.
CDC25A is required for progression through G1 and S phases and activates cyclin-dependent kinase CDC2 by removing two phosphate groups.
CDC25A is degraded in response to DNA damage to prevent abnormal cell division and is considered an oncogene, though its role in oncogenesis is not fully defined.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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