
Thermo Fisher Scientific EFCAB4A Polyclonal Antibody
Thermo Fisher Scientific의 EFCAB4A Polyclonal Antibody는 인간 EFCAB4A 단백질을 인식하는 토끼 유래 IgG 항체입니다. Western blot 및 IHC(P)에서 검증되었으며, 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용되며 장기 보관 시 -20°C에서 보관합니다.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human EFCAB4A. Recombinant protein control fragment (Product #RP-97506). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.4 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2640908 |
Product Specific Information
Immunogen sequence:
LEAVFESLDQ AHTGFLTARE FCLGLGMFVG VASAQGANPC RTPEETFESG GLDVQGTAGS LDEE
Highest antigen sequence identity to orthologs:
- Mouse: 77%
- Rat: 77%
Target Information
EFCAB4A, also known as Calcium release-activated calcium channel regulator 2B, is a novel Ca²⁺-binding EF-hand protein that is thought to play a key role in store-operated Ca²⁺ entry in T-cells by regulating CRAC channel activation. Its detailed function is still under investigation. It is likely to play a similar role as EFCAB4B, which acts as a cytoplasmic calcium sensor forming a complex with ORAI1 and STIM1 at junctional regions between the plasma membrane and endoplasmic reticulum upon low Ca²⁺ concentration.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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