Thermo Fisher Scientific S100A10 Polyclonal Antibody
인간 S100A10 단백질을 인식하는 Rabbit Polyclonal Antibody로 다양한 응용 분야(WB, IHC, ICC, ELISA)에 사용 가능. 고순도 Protein A 정제, 1 mg/mL 농도, 안정적인 액상 형태. 연구용으로만 사용 가능.
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Thermo Fisher Scientific S100A10 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human S100A10, amino acids 21–97 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The S-100 family of calcium-activated proteins interacts with various target proteins to modulate biological signaling pathways. Numerous cancer cell lines overexpress the plasminogen receptor S-100A10 on the extracellular cell surface, where it forms a heterotetrameric complex with Annexin II. This association is not required for plasma membrane localization or plasminogen activation. Additionally, S-100A10 acts as a cellular chaperone for hepatitis B virus polymerase, facilitating its nuclear localization and potentially influencing viral replication.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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