Thermo Fisher Scientific MKK4 Polyclonal Antibody
MKK4 단백질을 인식하는 Thermo Fisher의 폴리클로날 항체로, Western blot 및 Immunoprecipitation에 적합합니다. 사람과 생쥐 시료에 반응하며, 항원 친화 크로마토그래피로 정제된 비결합 액상 항체입니다. 세포 스트레스 및 염증 반응 연구에 유용합니다.
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- pk
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunoprecipitation (IP) | 2–5 µg/mg lysate |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 349 and 399 of human dual specificity mitogen-activated protein kinase kinase 4 (MAP2K4, UniProt ID: P45985-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | Tris citrate/phosphate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage conditions | 4°C |
| Shipping conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
MAP2K4 (MEK4) is a dual specificity serine/threonine kinase of the STE7 family that phosphorylates and activates JNK1/2 and p38. It preferentially phosphorylates the tyrosine residue of JNKs and is involved in responses to cellular stress and inflammatory cytokines.
MAP2K4 plays roles in carcinogenesis; loss-of-function mutations have been observed in lung and pancreatic tumors, while pro-oncogenic activity has also been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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