Thermo Fisher Scientific Phospho-LRP1 (Ser4523) Polyclonal Antibody
Phospho-LRP1 (Ser4523) 특이적 폴리클로날 항체로 인간, 마우스, 랫트에 반응합니다. 다양한 면역실험(IHC, ICC, Flow, ELISA)에 적합하며, 고순도 Protein A 정제 및 안정적 액상 형태로 제공됩니다. 연구용으로 Alzheimer 관련 단백질 연구에 활용 가능합니다.
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Thermo Fisher Scientific Phospho-LRP1 (Ser4523) Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| Flow Cytometry (Flow) | 1:20–1:100 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic phosphopeptide derived from human LRP1 around the phosphorylation site of Ser4523 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The protein encoded by this gene is an endocytic receptor involved in several cellular processes, including intracellular signaling, lipid homeostasis, and clearance of apoptotic cells. It is necessary for the A2M-mediated clearance of secreted amyloid precursor protein and beta-amyloid, the main component of amyloid plaques found in Alzheimer patients. Expression of this gene decreases with age and is lower in brain tissue from Alzheimer patients compared to controls.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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