Thermo Fisher Scientific SYP Monoclonal Antibody (OTI1A1), TrueMAB
Synaptophysin 단백질을 인식하는 인간 반응성 Mouse monoclonal 항체. Western blot 및 Immunocytochemistry에 사용 가능. 동결건조 형태로 공급되며, 재구성 시 1 mg/mL 농도 권장. 신경 말단 및 신경내분비 종양 표지 연구에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1A1 |
| Immunogen | Full length human recombinant protein of human SYP produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882) to ensure carrier-free conditions.
Target Information
Synaptophysin is a calcium-binding integral membrane glycoprotein found in presynaptic vesicles of nearly all neurons.
It contains four transmembrane domains and forms a complex with dynamin under high calcium conditions, indicating a role in synaptic vesicle endocytosis.
Synaptophysin is involved in short- and long-term synaptic plasticity regulation and is widely used as a marker for nerve terminals and neuroendocrine tumors.
Mutations in the gene are associated with X-linked mental retardation.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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