Thermo Fisher Scientific PEG (methoxy group) Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:5,000–1:200,000

Product Specifications

Product Specific Information

• Store as concentrated solution.
• Centrifuge briefly before opening the vial.
• For short-term storage (1–2 weeks), store at 4°C.
• For long-term storage, aliquot and store at -20°C or below.
• Avoid multiple freeze-thaw cycles.

Target Information

PEG recruits the serine/threonine-protein phosphatase PP1 to dephosphorylate the translation initiation factor eIF-2A/EIF2S1, reversing the shut-off of protein synthesis initiated by stress-inducible kinases and facilitating recovery of cells from stress.
It down-regulates the TGF-beta signaling pathway by promoting dephosphorylation of TGFB1 by PP1 and may promote apoptosis by inducing TP53 phosphorylation on Ser-15.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.