Thermo Fisher Scientific Phospho-PGC (Ser15) Polyclonal Antibody

Applications

• Western Blot (WB): 1:1,000–1:2,000

Product Specifications

Product Specific Information

This antibody is predicted to react with human based on sequence homology.

Target Information

Pepsin is one of the main proteolytic enzymes secreted by the gastric mucosa. It consists of a single polypeptide chain and arises from its precursor, pepsinogen, by removal of a 41 amino acid segment from the N-terminus. Pepsinogen is synthesized in the stomach lining, and hydrochloric acid is necessary to convert the inactive enzyme and maintain the optimum acidity (pH 1–3) for pepsin function. Pepsin effectively cleaves peptide bonds involving aromatic amino acids and shows broad specificity, with preference for bonds involving phenylalanine and leucine. The amino acid composition of Pepsin C differs from those of pepsinogen and pepsin, particularly in the content of basic amino acids, glutamic acid, aspartic acid, leucine, and isoleucine.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.