
Thermo Fisher Scientific Integrin beta 3 Polyclonal Antibody
Integrin beta 3 (CD61) 단백질을 인식하는 Rabbit Polyclonal 항체로, Human 및 Mouse 시료에서 WB, IHC, ICC, Flow, ELISA 등 다양한 응용에 사용 가능. Protein A로 정제되었으며, -20°C에서 보관. 연구용 시약.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:300 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:200 |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| Flow Cytometry (Flow) | 1:50 |
| ELISA | 1:5,000–1:10,000 |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide derived from human Integrin beta 3 (amino acids 27–120) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS (pH 7.4) with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
CD61 (GPIIIa, ITGB3) is a glycoprotein found on megakaryocytes, platelets, and their precursors. It plays a role in platelet aggregation and serves as a receptor for fibrinogen, fibronectin, von Willebrand factor, and vitronectin.
CD61 (105 kDa) associates with either alpha IIb integrin (CD41) or alpha V integrin (CD51) at the cell surface. It is expressed on platelets, megakaryocytes, endothelial cells, monocytes, and osteoclasts.
CD61 participates in cell adhesion and cell-surface mediated signaling. Dysfunctions are associated with Glanzmann Thrombasthenia and Platelet type-16 Bleeding Disorder.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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