Thermo Fisher Scientific EGR2 Recombinant Rabbit Monoclonal Antibody (ARC1932)
EGR2 단백질을 인식하는 Recombinant Rabbit Monoclonal Antibody로, Western blot, ELISA, IP에 적합합니다. 인간, 마우스, 랫트 시료에 반응하며, HEK293 세포에서 발현되었습니다. 고순도의 Affinity chromatography 정제 항체로 연구용에 적합합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1 µg/mL |
| Immunoprecipitation (IP) | 0.5–4 µg antibody for 400–600 µg extracts |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ARC1932 |
| Immunogen | Synthetic peptide corresponding to amino acids 1–100 of human EGR2 (NP_000390.2) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2897971 |
Product Specific Information
- Positive Samples: PC-3, SH-SY5Y, Mouse brain, Rat brain
- Immunogen Sequence:
MMTAKAVDKI PVTLSGFVHQ LSDNIYPVED LAATSVTIFP NAELGGPFDQ MNGVAGDGMI NIDMTGEKRS LDLPYPSSFA PVSAPRNQTF TYMGKFSIDP
Target Information
The EGR2 gene encodes the early growth response 2 protein, a transcription factor that binds specific DNA regions to regulate gene activity.
This protein is critical for the formation and maintenance of myelin, the insulating layer around nerve cells that ensures efficient nerve impulse transmission.
Mutations in the EGR2 gene can lead to Charcot-Marie-Tooth disease type 1D or 4E, and severe forms such as Dejerine-Sottas syndrome, which manifest in infancy or early childhood.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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