Thermo Fisher Scientific NGFR Monoclonal Antibody (4G5)

Applications

Tested Dilution

Publications

ELISA (ELISA)

10 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1, kappa

Class

Monoclonal

Type

Antibody

Clone

4G5

Immunogen

NGFR (AAH50309.1, 65 a.a. approximately 148 a.a) partial recombinant protein with mouse IgG2a-Fc tag. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:NGFR (CD271),uniProtId:P08138-1,ncbiNodeId:9606,antigenRange:65-148,antigenLength:427,antigenImageFileName:H00004804-M05_NGFR_CD271_P08138-1_House_mouse.svg,antigenImageFileNamePDP:H00004804-M05_NGFR_CD271_P08138-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: EPCLDSVTFS DVVSATEPCK PCTECVGLQS MSAPCVEADD AVCRCAYGYY QDETTGRCEA CRVCEAGSGL VFSCQDKQNT VCEEGGGGS

Target Information

Neurotrophic factors control the survival, differentiation and maintenance of neurons in the peripheral and central nervous systems, and of other neural crest-derived cell types. Developing sympathetic neurons are absolutely dependent upon nerve growth factor (NGF) during the period of target competition in vivo. Antibodies reacting specifically with NGFR p75 are useful tools in the detection and characterization of NGFR p75, to enhance our understanding of a wide range of phenomena in the development, plasticity and repair of the nervous system.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.