Thermo Fisher Scientific EHMT1 Polyclonal Antibody
EHMT1 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, Western blot에 적합합니다. Rabbit IgG 기반으로 제작되었으며, 고순도의 액상 형태로 제공됩니다. 인체 EHMT1 중심부(aa 367–396)에서 유래한 면역원 사용. 연구용으로만 사용 가능합니다.
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- PA511135
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Applications
Tested Application and Dilution
- Western Blot (WB): 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide corresponding to amino acids 367–396 of the central region of human EHMT1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2 mg/mL |
| Purification | Size-exclusion chromatography, dialysis, ammonium sulfate precipitation |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C for short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2246416 |
Target Information
EHMT1 (also known as EUHMTASE1) is a histone methyltransferase that methylates Lys-9 of histone H3 in vitro. H3 Lys-9 methylation acts as an epigenetic transcriptional repression mark by recruiting HP1 proteins to methylated histones. EHMT1 is likely targeted to histone H3 by DNA-binding proteins such as E2F6, MGA, MAX, and/or DP1. During the G0 phase, it contributes to the silencing of MYC- and E2F-responsive genes, suggesting a role in the G0/G1 transition of the cell cycle.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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