Thermo Fisher Scientific Kir2.3 (KCNJ4) Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 50-150 of human KCNJ4 (NP_0049721) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Kir2.3 (KCNJ4),uniProtId:P48050-1,ncbiNodeId:9606,antigenRange:50-150,antigenLength:445,antigenImageFileName:PA5-89575_Kir2.3_KCNJ4_P48050-1_Rabbit.svg,antigenImageFileNamePDP:PA5-89575_Kir2.3_KCNJ4_P48050-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.6 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2805663

Product Specific Information

Immunogen sequence: CVDTRWRYML MIFSAAFLVS WLFFGLLFWC IAFFHGDLEA SPGVPAAGGP AAGGGGAAPV APKPCIMHVN GFLGAFLFSV ETQTTIGYGF RCVTEECPLA V; Positive Samples: SKOV3, Mouse skeletal muscle, Rat kidney; Cellular Location: Cell junction, Cell membrane, Cytoplasmic vesicle membrane, Multi-pass membrane protein, postsynaptic cell membrane, synapse

Target Information

Several different potassium channels are known to be involved with electrical signaling in the nervous system. One class is activated by depolarization whereas a second class is not. The latter are referred to as inwardly rectifying K+ channels, and they have a greater tendency to allow potassium to flow into the cell rather than out of it. This asymmetry in potassium ion conductance plays a key role in the excitability of muscle cells and neurons. The protein encoded by this gene is an integral membrane protein and member of the inward rectifier potassium channel family. The encoded protein has a small unitary conductance compared to other members of this protein family. Two transcript variants encoding the same protein have been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.