Thermo Fisher Scientific Kir2.3 (KCNJ4) Polyclonal Antibody
Kir2.3(KCNJ4) 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC, ELISA에 사용 가능. Human, Mouse, Rat 반응성. Affinity Chromatography로 정제된 액상 형태이며, 세포막 및 시냅스 단백질 연구에 적합.
- 판매단위
- pk
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 50–150 of human KCNJ4 (NP_004972.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.6 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2805663 |
Product Specific Information
- Immunogen sequence:
CVDTRWRYML MIFSAAFLVS WLFFGLLFWC IAFFHGDLEA SPGVPAAGGP AAGGGGAAPV APKPCIMHVN GFLGAFLFSV ETQTTIGYGF RCVTEECPLA V - Positive Samples: SKOV3, Mouse skeletal muscle, Rat kidney
- Cellular Location: Cell junction, Cell membrane, Cytoplasmic vesicle membrane, Multi-pass membrane protein, postsynaptic cell membrane, synapse
Target Information
Inwardly rectifying potassium channels (Kir) are involved in electrical signaling in the nervous system. Unlike depolarization-activated channels, these channels preferentially allow potassium ions to flow into the cell, contributing to the excitability of muscle cells and neurons.
The KCNJ4 gene encodes an integral membrane protein belonging to the inward rectifier potassium channel family, characterized by relatively small unitary conductance. Two transcript variants encoding the same protein have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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