Thermo Fisher Scientific RASSF1 Monoclonal Antibody (OTI8A11), TrueMAB
RASSF1 단백질을 표적으로 하는 Thermo Fisher Scientific의 Mouse Monoclonal Antibody (Clone OTI8A11). Western blot 및 Immunocytochemistry에 최적화. Human 반응성, Lyophilized 형태, 높은 순도의 Affinity chromatography 정제 제품.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI8A11 |
| Immunogen | Full length human recombinant protein of human RASSF1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step.
Recommended product: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL (Product #89882).
Target Information
RASSF1 encodes a protein similar to RAS effector proteins. Altered expression or loss of this gene is associated with various cancers, suggesting a tumor suppressor role. Inactivation is correlated with hypermethylation of its CpG-island promoter region. The protein interacts with DNA repair protein XPA and inhibits cyclin D1 accumulation, inducing cell cycle arrest. Seven alternatively spliced transcript variants encoding distinct isoforms have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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