Thermo Fisher Scientific LEPREL1 Polyclonal Antibody
Human 및 Rat 반응성을 가진 LEPREL1 폴리클로날 항체로, Western blot 및 IHC(P) 분석에 적합. 항원 친화 크로마토그래피로 정제된 고순도 항체. PBS buffer와 glycerol 함유, 안정적인 보관 가능. 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 0.04–0.4 µg/mL
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human LEPREL1. Recombinant protein control fragment (Product #RP-89685) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2643344 |
Product Specific Information
Immunogen sequence:
LHYDYLQFAY YRVGEYVKAL ECAKAYLLCH PDDEDVLDNV DYYESLLDDS IDPASIEARE DLTMFVKRHK LESELIKSAA EGLGFSYTEP NYWIRYGGRQ DENRVPSGVN VEGAEVHGFS MGKKLSPKID RDLREGGPLL Y
Highest antigen sequence identity to the following orthologs:
- Mouse: 89%
- Rat: 89%
Target Information
This gene encodes a member of the prolyl 3-hydroxylase subfamily of 2-oxo-glutarate-dependent dioxygenases. These enzymes play a critical role in collagen chain assembly, stability, and cross-linking by catalyzing post-translational 3-hydroxylation of proline residues.
Mutations in this gene are associated with nonsyndromic severe myopia with cataract and vitreoretinal degeneration, and downregulation of this gene may play a role in breast cancer.
Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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