Thermo Fisher Scientific Phospho-SHIP2 (Tyr986, Tyr987) Polyclonal Antibody
Phospho-SHIP2 (Tyr986, Tyr987) 항체로 인산화된 INPPL1 단백질을 특이적으로 검출. Western blot 및 IHC(P) 실험에 적합. Rabbit IgG 폴리클로날 형식으로 높은 특이성과 재현성 제공. 연구용으로만 사용 가능.
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Thermo Fisher Scientific Phospho-SHIP2 (Tyr986, Tyr987) Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human INPPL1 (Accession O15357), corresponding to amino acid residues around phosphorylated Tyr986 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2816127 |
Product Specific Information
Antibody detects endogenous levels of INPPL1 only when phosphorylated at Tyr986/987.
Target Information
The protein encoded by this gene is an SH2-containing 5'-inositol phosphatase that is involved in the regulation of insulin function.
It also plays a role in the regulation of epidermal growth factor receptor turnover and actin remodeling.
Additionally, this gene supports metastatic growth in breast cancer and is a valuable biomarker for breast cancer.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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