Thermo Fisher Scientific PCDH11Y Monoclonal Antibody (7D12)

Applications

Tested Dilution

Publications

Western Blot (WB)

1-5 µg/mL

-

ELISA (ELISA)

0.3 ng/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG2a, kappa

Class

Monoclonal

Type

Antibody

Clone

7D12

Immunogen

PCDH11Y (NP_004733, 57 a.a. approximately 165 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:PCDH11Y,uniProtId:Q9BZA8-1,ncbiNodeId:9606,antigenRange:57-165,antigenLength:1340,antigenImageFileName:H00083259-M02_PCDH11Y_Q9BZA8-1_House_mouse.svg,antigenImageFileNamePDP:H00083259-M02_PCDH11Y_Q9BZA8-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: EKNYTIREEI PENVLIGNLL KDLNLSLIPN KSLTTTMQFK LVYKTGDVPL IRIEEDTGEI FTTGARIDRE KLCAGIPRDE HCFYEVEVAI LPDEIFRLVK IRFLIEDIN

Target Information

This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. The encoded protein consists of an extracellular domain containing 7 cadherin repeats, a transmembrane domain and a cytoplasmic tail that differs from those of the classical cadherins. The gene is located in a major X/Y block of homology and its most closely related cadherin superfamily member is located in this homologous region on the X chromosome. The protein is thought to play a fundamental role in cell-cell recognition essential for the segmental development and function of the central nervous system. Transcripts arising from alternative splicing encode isoforms with N- and C-terminal variation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.