Thermo Fisher Scientific C17orf37 Monoclonal Antibody (OTI4D6), TrueMAB
C17orf37 단백질을 인식하는 Mouse monoclonal antibody로, Western blot에 최적화되어 있습니다. Human 시료에 반응하며, Lyophilized 형태로 제공됩니다. Affinity chromatography로 정제되었고, 재구성 후 1 mg/mL 농도로 사용 가능합니다. 연구용으로만 사용하십시오.
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Applications
- Western Blot (WB): Tested dilution 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4D6 |
| Immunogen | Full length human recombinant protein of human C17orf37 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
The ERBB2 (neu/HER2) oncogene is a key predictor of patient outcomes and therapeutic responses in breast cancer.
C35 (C17orf37) is a novel tumor biomarker highly expressed in breast cancer. It is located on chromosome 17q12, approximately 505 nucleotides from the 3′ end of the ERBB2 oncogene—the target for trastuzumab (Herceptin) therapy.
The genes encoding C35 and ERBB2 are arranged tail-to-tail. The ORF 37 open reading frame encodes a 12-kDa protein of unknown function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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