Thermo Fisher Scientific PURA Monoclonal Antibody (1D6)
PURA 단백질을 인식하는 Mouse monoclonal antibody(1D6)로, WB, ICC/IF, ELISA에 적합합니다. 비결합(Unconjugated) 형식의 액상 제품이며, -20°C에서 보관합니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| Immunocytochemistry (ICC/IF) | 10 µg/mL |
| ELISA | 10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1D6 |
| Immunogen | PURA (NP_005850, 183 a.a. ~ 292 a.a) partial recombinant protein with GST tag. MW of GST tag alone: 26 kDa |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
TQGQTIALPA QGLIEFRDAL AKLIDDYGVE EEPAELPEGT SLTVDNKRFF FDVGSNKYGV FMRVSEVKPT YRNSITVPYK VWAKFGHTFC KYSEETKKIQ EKQREKRAAC
Target Information
This gene product is a sequence-specific, single-stranded DNA-binding protein. It binds preferentially to the single strand of the purine-rich element termed PUR, which is present at origins of replication and in gene flanking regions in a variety of eukaryotes from yeasts through humans. Thus, it is implicated in the control of both DNA replication and transcription. Deletion of this gene has been associated with myelodysplastic syndrome and acute myelogenous leukemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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