Thermo Fisher Scientific PURA Monoclonal Antibody (1D6)

Applications

Tested Dilution

Publications

Western Blot (WB)

1-5 µg/mL

-

Immunocytochemistry (ICC/IF)

10 µg/mL

-

ELISA (ELISA)

10 µg/mL

-

Product Specifications

Host/Isotype

Mouse / IgG2b, kappa

Class

Monoclonal

Type

Antibody

Clone

1D6

Immunogen

PURA (NP_005850, 183 a.a. approximately 292 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:PURA,uniProtId:Q00577-1,ncbiNodeId:9606,antigenRange:183-292,antigenLength:322,antigenImageFileName:H00005813-M07_PURA_Q00577-1_House_mouse.svg,antigenImageFileNamePDP:H00005813-M07_PURA_Q00577-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: TQGQTIALPA QGLIEFRDAL AKLIDDYGVE EEPAELPEGT SLTVDNKRFF FDVGSNKYGV FMRVSEVKPT YRNSITVPYK VWAKFGHTFC KYSEETKKIQ EKQREKRAAC

Target Information

This gene product is a sequence-specific, single-stranded DNA-binding protein. It binds preferentially to the single strand of the purine-rich element termed PUR, which is present at origins of replication and in gene flanking regions in a variety of eukaryotes from yeasts through humans. Thus, it is implicated in the control of both DNA replication and transcription. Deletion of this gene has been associated with myelodysplastic syndrome and acute myelogenous leukemia.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.