Thermo Fisher Scientific GABRA5 Polyclonal Antibody
Rabbit polyclonal antibody targeting GABRA5 for detection in WB and IHC applications. Reacts with mouse and human samples. High specificity via antigen affinity purification. Supplied in liquid form with glycerol and BSA for stability. For research use...
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:3,000 | View 2 publications |
| Immunohistochemistry (IHC) | – | View 2 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 | View publications |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Mouse, Human |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to amino acids 142–379 of Human GABA A Receptor alpha 5 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.21 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol, 1% BSA |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C (short term). For long-term storage, store at −20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2548637 |
Product Specific Information
- Recommended positive control: GABRA5-transfected 293T cells
- Predicted reactivity: Mouse (100%), Rat (100%), Bovine (98%)
- Store product as a concentrated solution. Centrifuge briefly before opening the vial.
Target Information
GABRA5 is a component of GABA, a major inhibitory neurotransmitter in the mammalian brain that acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines binding to the GABA-A receptor.
At least 16 distinct subunits of GABA-A receptors have been identified. Transcript variants utilizing three different alternative non-coding first exons have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일: PA5-31163_GABRA5_P31644-1_Rabbit.svg, PA5-31163_GABRA5_P31644-1_Rabbit_PDP.jpeg)
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