Thermo Fisher Scientific FNIP1 Polyclonal Antibody
Thermo Fisher Scientific의 FNIP1 Polyclonal Antibody는 인간 FNIP1 단백질을 인식하는 토끼 유래 다클론 항체입니다. Western blot 및 Immunoprecipitation에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. 세포 대사 및 AMPK 신호 조절 연구에 활용됩니다.
- 카탈로그번호
- A305-767A
- 판매단위
- pk
카탈로그
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunoprecipitation (IP) | 20 µL/mg of lysate |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A region between residue 775 to 825 of human Folliculin-interacting protein 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | phosphate/tris citrate, pH 7.0–8.0 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
FNIP1 encodes a protein that binds to the tumor suppressor protein folliculin and to AMP-activated protein kinase (AMPK). The encoded protein participates in the regulation of cellular metabolism and nutrient sensing by modulating the AMPK and target of rapamycin signaling pathways.
This gene has a closely related paralog that encodes a protein with similar binding activities. Both related proteins also associate with the molecular chaperone heat shock protein-90 (Hsp90), negatively regulate its ATPase activity, and facilitate its association with folliculin.
Diseases associated with FNIP1 include Birt-Hogg-Dube Syndrome and Pleural Disease.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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