
Thermo Fisher Scientific SEC61A1 Polyclonal Antibody
SEC61A1 단백질을 인식하는 Thermo Fisher Scientific의 rabbit polyclonal antibody. WB 및 ICC/IF에서 사용 가능하며, 인간, 마우스, 원숭이, 랫트 반응성. 액상 형태로 1 mg/mL 농도, PBS+50% glycerol 보관, -20°C 저장.
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Thermo Fisher Scientific SEC61A1 Polyclonal Antibody
Applications and Tested Dilution
- Western Blot (WB): 1:500–1:2,000
- Immunocytochemistry (ICC/IF): 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human SEC61A1 (Accession P61619), corresponding to amino acid residues S443–F476 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2900513 |
Product Specific Information
Antibody detects endogenous levels of total SEC61A.
Target Information
The Sec61 complex is responsible for translocation of proteins across the rough endoplasmic reticulum membrane. It consists of three subunits—alpha, beta, and gamma—that form a heterotrimer. Multiple heterotrimers associate to form the ER translocon. Sec61 alpha is a polytopic protein with ten membrane-spanning loops. It is tightly associated with membrane-bound ribosomes and is essential for assembly of membrane and secretory proteins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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