Thermo Fisher Scientific CRYBB2 Polyclonal Antibody
CRYBB2 단백질을 검출하는 Thermo Fisher Scientific의 다클론 항체로 인간, 생쥐, 랫트에 반응합니다. Western blot 및 IHC(P) 실험에 적합하며, 고순도 친화 크로마토그래피 정제 제품입니다. 액상 형태로 -20°C 보관하며 연구용으로 사용됩니다.
- 카탈로그번호
- PA5102805
- 판매단위
- pk
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Thermo Fisher Scientific CRYBB2 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human CRYBB2 (Accession P43320), corresponding to amino acid residues G61–L111 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2852196 |
Product Specific Information
Antibody detects endogenous levels of total CRYBB2.
Target Information
Crystallins are separated into two classes: taxon-specific (enzyme) and ubiquitous. The ubiquitous class constitutes the major proteins of the vertebrate eye lens, maintaining transparency and refractive index. Lens fiber cells lose their nuclei during development, and crystallins remain stable throughout life. Mammalian lens crystallins are divided into alpha, beta, and gamma families.
Beta-crystallins, the most heterogeneous, differ by the presence of a C-terminal extension. They can self-associate to form dimers or heterodimers with other beta-crystallins.
The CRYBB2 gene, a beta basic group member, is part of a gene cluster with beta-A4, beta-B1, and beta-B3. A chain-terminating mutation in this gene is associated with type 2 cerulean cataracts.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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