Thermo Fisher Scientific GNPNAT1 Polyclonal Antibody
GNPNAT1 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot에 적합합니다. 인간, 마우스, 랫트 시료에 반응하며, Affinity chromatography로 정제되었습니다. PBS/glycerol buffer에 보관되며 -20°C에서 안정적으로 저장 가능합니다.
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- PA5100547
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Applications
- Western Blot (WB): 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human GNPNAT1 (Accession Q96EK6), corresponding to amino acid residues E5–K55 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2850056 |
Product Specific Information
This antibody detects endogenous levels of total GNPNAT1.
Target Information
Glucosamine-6-phosphate-N-acetyl Transferase (GNPNAT1) is a key enzyme in the hexosamine biosynthetic pathway. It catalyzes the conversion of D-glucosamine 6-phosphate to N-acetyl-D-glucosamine 6-phosphate, enabling carbon and nitrogen to enter the hexosamine biosynthetic pathway. Inhibition of GNPNAT1 has been reported to promote proliferation and aggressiveness in castration-resistant prostate cancer (PMID: 27194471).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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