Thermo Fisher Scientific 3pK Polyclonal Antibody
MAPKAPK3 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot에 적합합니다. 액상형으로 제공되며 4°C에서 보관합니다. 연구용으로만 사용되며, 세포 신호전달 및 스트레스 반응 연구에 활용됩니다.
- 판매단위
- pk
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Applications
- Western Blot (WB)
Tested Dilution: 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Between 1 and 50 of MAPKAPK3 (UniProt ID: Q16644-1, NCBI Node ID: 9606, Antigen Length: 382) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.40 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
Target Information
MAPKAPK3 functions as an integrative element of signaling in both mitogen and stress responses. It acts as a mitogen-activated protein kinase (MAP kinase)-activated protein kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), serve as integration points for multiple biochemical signals.
MAPKAPK3 is activated by growth inducers and stress stimulation of cells. In vitro studies have shown that ERK, p38 MAP kinase, and Jun N-terminal kinase can phosphorylate and activate this kinase, suggesting its role as an integrative signaling element.
MAPKAPK3 interacts with, phosphorylates, and represses the activity of E47, a transcription factor involved in tissue-specific gene expression and cell differentiation.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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