Thermo Fisher Scientific Calbindin D28K Recombinant Rabbit Monoclonal Antibody (HL2379)
Calbindin D28K 단백질을 표적하는 재조합 토끼 단일클론 항체로, Western blot, IHC, ICC 등 다양한 응용에 적합. 인간, 마우스, 랫트 반응성. HEK293 발현 시스템 사용, Protein A 정제, PBS 버퍼에 보존. 연구용 전용 제품.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | HL2379 |
| Immunogen | Recombinant fragment of human Calbindin |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3094224 |
Target Information
Calbindin-D-28K (also termed vitamin D-dependent calcium-binding protein, or cholecalcin) is a highly conserved 28 kDa calcium-binding protein with broad tissue distribution. It belongs to the family of low molecular weight calcium-binding proteins (CaBPs), including calmodulin, S-100, parvalbumin, and troponin C. These CaBPs share homologous primary structures containing conserved EF-hand type polypeptide folds for Ca²⁺ binding.
Calbindin-D-28K is predominantly found in subpopulations of neurons in the central and peripheral nervous systems, as well as in epithelial cells involved in calcium transport such as distal tubular cells and cortical collecting tubules of the kidney, and in enteric neuroendocrine cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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