Thermo Fisher Scientific Slc30A8 Polyclonal Antibody
Rabbit polyclonal antibody against human Slc30A8, validated for Western blot. Recognizes amino acids 263–369 of the target protein. Supplied as a liquid, unconjugated form with 0.5 mg/mL concentration. Suitable for research use only.
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Applications
Western Blot (WB)
- Tested dilution: 0.5–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein of Solute Carrier Family 30 Member 8 (amino acids 263–369) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2903924 |
Target Information
Slc30A8 is a zinc efflux transporter involved in the accumulation of zinc in intracellular vesicles. It is highly expressed in the pancreas, particularly in the islets of Langerhans, and co-localizes with insulin in the secretory granules of insulin-secreting INS-1 cells.
Allelic variants of Slc30A8 are major genetic risk factors for Type 2 diabetes, though no association has been found with Type 1 diabetes. Expression in β-cells is influenced by cytokines such as IFN-gamma and IL-1 beta.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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