Thermo Fisher Scientific MST4 Polyclonal Antibody
Human MST4 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P) 실험에 1:500~1:1,000 희석 비율로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며 PBS/glycerol buffer에 보존. MST4 단백질의 발현 및 기능 연구용으로 적합.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Protein corresponding to Human MST4. Recombinant protein control fragment (Product #RP-103363). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2856907 |
Product Specific Information
Immunogen sequence:
GHSDDESDSE GSDSESTSRE NNTHPEWSFT TVRKKPDPKK VQNGAEQDLV QTLSCLSMII TPAFAELKQQ DENNA
Target Information
MST4 is a member of the Ste20-like kinase family of serine/threonine kinases and is overexpressed during prostate cancer development. The product of this gene belongs to the GCK group III family of kinases, a subset of Ste20-like kinases.
The encoded protein contains:
- An amino-terminal kinase domain
- A carboxy-terminal regulatory domain mediating homodimerization
MST4 localizes to the Golgi apparatus and is activated by binding to the Golgi matrix protein GM130. It is cleaved by caspase-3 in vitro and may function in the apoptotic pathway. Several alternatively spliced transcript variants have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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