Thermo Fisher Scientific EDD1 Polyclonal Antibody
Rabbit polyclonal antibody targeting human E3 ubiquitin-protein ligase (EDD1). Suitable for IHC and IHC(P) at 1:100–1:500 dilution. Cross-reacts with multiple species. Stored at 4°C, purified by antigen affinity chromatography.
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Applications
Immunohistochemistry (IHC)
- Tested Dilution: 1:100–1:500
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 600 and 650 of human E3 Ubiquitin Protein Ligase, HECT domain containing 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.10 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | TBS, pH 7.0–8.0, with 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Mouse, Rat, X. tropicalis, Chicken, Turkey, Bovine, Dog, Horse, Pig, Panda, Orangutan, Monkey, Gorilla, and Chimpanzee
Target Information
EDD (E3 identified by Differential Display) is a progestin-regulated gene isolated from T-47D human breast cancer cells. Based on sequence homology, EDD is a human homolog of the Drosophila hyperplastic discs (hyd) gene, a tumor suppressor required for control of imaginal disc growth.
EDD contains a HECT domain in the carboxy terminus. HECT domain-containing proteins function as ubiquitin-protein ligases (E3 enzymes). EDD binds to ubiquitin and, like other HECT family proteins, may function as an E3 ubiquitin-protein ligase.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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