Thermo Fisher Scientific IGF2 Polyclonal Antibody, MaxPab
IGF2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody입니다. Western blot에 적합하며 인간 시료에 반응합니다. 고순도 Affinity chromatography로 정제된 액상형 항체로, PBS buffer에 보존됩니다. 연구용으로만 사용 가능합니다.
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Applications
- Western Blot (WB): Tested dilution 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | IGF2 (NP_000603.1, 1 a.a. – approximately 180 a.a) full-length human protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
MGIPMGKSML VLLTFLAFAS CCIAAYRPSE TLCGGELVDT LQFVCGDRGF YFSRPASRVS RRSRGIVEEC CFRSCDLALL ETYCATPAKS ERDVSTPPTV LPDNFPRYPV GKFFQYDTWK QSTQRLRRGL PALLRARRGH VLAKELEAFR EAKRHRPLIA LPTQDPAHGG APPEMASNRK
Target Information
The IGFs are mitogenic, polypeptide growth factors that stimulate proliferation and survival of various cell types, including muscle, bone, and cartilage tissue in vitro. IGFs are predominantly produced by the liver, though various tissues also produce them at distinctive times.
IGFs belong to the Insulin gene family, which includes insulin and relaxin. They are structurally and functionally similar to insulin but have stronger growth-promoting activity.
IGF-II expression is influenced by placenta lactogen, while IGF-I expression is regulated by growth hormone. Both IGF-I and IGF-II signal through the tyrosine kinase type I receptor (IGF-IR), and IGF-II can also signal through the IGF-II/Mannose-6-phosphate receptor. Mature IGFs are generated by proteolytic processing of inactive precursor proteins containing N-terminal and C-terminal propeptide regions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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