Thermo Fisher Scientific ACE Monoclonal Antibody (3.1.1)
ACE 단백질을 인식하는 Mouse IgM 단일클론 항체로, Human, Bovine, Mouse, Rat 시료에 반응합니다. ELISA, IHC, Flow Cytometry에 사용 가능하며, 0.7 mg/mL 농도의 액상 형태입니다. 연구용으로 혈압 및 레닌-안지오텐신 시스템 관련 연구에 적합합니다.
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Applications
| Application | Tested Dilution | Reference |
|---|---|---|
| Immunohistochemistry (IHC) | 1–10 µg/mL | - |
| Flow Cytometry (Flow) | 1–10 µg/mL | - |
| ELISA | 1–10 µg/mL | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bovine, Human, Mouse, Rat |
| Host / Isotype | Mouse / IgM |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3.1.1 |
| Immunogen | Angiotensin converting enzyme purified from rat lung |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.7 mg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10985105 |
Product Specific Information
MA1-10822 detects Angiotensin Converting Enzyme (ACE) from human, bovine, and mouse samples.
It has been successfully used in ELISA, immunohistochemistry, and flow cytometry applications.
The immunogen is angiotensin converting enzyme purified from rat lung.
Target Information
This gene encodes an enzyme that catalyzes the conversion of angiotensin I into angiotensin II, a physiologically active peptide.
Angiotensin II acts as a potent vasopressor and aldosterone-stimulating peptide, regulating blood pressure and fluid-electrolyte balance.
The enzyme plays a key role in the renin-angiotensin system.
Studies have linked a 287 bp Alu repeat element in this gene to circulating enzyme levels and cardiovascular pathophysiologies.
Two main alternatively spliced variants encode somatic and testicular forms, both active.
Additional splice variants have been identified, though their full-length nature is undetermined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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