Thermo Fisher Scientific ACE Monoclonal Antibody (3.1.1)

Applications

Product Specifications

Product Specific Information

MA1-10822 detects Angiotensin Converting Enzyme (ACE) from human, bovine, and mouse samples.
It has been successfully used in ELISA, immunohistochemistry, and flow cytometry applications.
The immunogen is angiotensin converting enzyme purified from rat lung.

Target Information

This gene encodes an enzyme that catalyzes the conversion of angiotensin I into angiotensin II, a physiologically active peptide.
Angiotensin II acts as a potent vasopressor and aldosterone-stimulating peptide, regulating blood pressure and fluid-electrolyte balance.
The enzyme plays a key role in the renin-angiotensin system.
Studies have linked a 287 bp Alu repeat element in this gene to circulating enzyme levels and cardiovascular pathophysiologies.
Two main alternatively spliced variants encode somatic and testicular forms, both active.
Additional splice variants have been identified, though their full-length nature is undetermined.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.