Thermo Fisher Scientific RRP9 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:50

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human RRP9. Recombinant protein control fragment (Product #RP-92413). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:RRP9,uniProtId:O43818-1,ncbiNodeId:9606,antigenRange:253-358,antigenLength:475,antigenImageFileName:PA5-58545_RRP9_O43818-1_Rabbit.svg,antigenImageFileNamePDP:PA5-58545_RRP9_O43818-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.05 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2646822

Product Specific Information

Immunogen sequence: THQLYSTSHD RSVKVWNVAE NSYVETLFGH QDAVAALDAL SRECCVTAGG RDGTVRVWKI PEESQLVFYG HQGSIDCIHL INEEHMVSGA DDGSVALWGL SKKRPL

Highest antigen sequence identity to the following orthologs: Mouse - 99%, Rat - 99%.

Target Information

The Ku autoantigen is a heterodimer of 70kDa (p70) and approximately 80kDa (p80) proteins. The p70/p80 dimer is important for function of a 460kDa DNA-dependent protein kinase that phosphorylates certain transcription factors, including Sp1, Oct-1, p53, and SV40 large T antigen in vitro. Ku protein plays a role in cell signaling, proliferation, DNA repair, replication, transcriptional activation, and apoptosis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.