Thermo Fisher Scientific TSEN15 Monoclonal Antibody (OTI3F5), TrueMAB

Applications

• Western Blot (WB): 1:250–1:500 dilution

Product Specifications

Target Information

Non-catalytic subunit of the tRNA-splicing endonuclease complex, responsible for identification and cleavage of splice sites in pre-tRNA. It cleaves pre-tRNA at the 5′ and 3′ splice sites to release the intron, producing two tRNA half-molecules with 2′,3′ cyclic phosphate and 5′-OH termini. Although splice site sequences are not conserved, the intron position is invariant, maintaining a constant distance from structural features of the tRNA body. The complex also participates in mRNA processing via association with pre-mRNA 3′-end processing factors, linking pre-tRNA splicing and mRNA 3′-end formation.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.