Thermo Fisher Scientific FOXP1 (Transcription Factor) Recombinant Rabbit Monoclonal Antibody (FOXP1, 44R)
FOXP1 전사인자를 인식하는 재조합 토끼 단클론 항체로, IHC(P) 검증 완료. 인간 시료 반응성, HEK293 발현 시스템 사용. Protein A/G 정제 및 PBS 기반 저장 완충액. 연구용 전용, 고특이성 및 재현성 높은 면역검출에 적합.
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Applications
Immunohistochemistry (Paraffin) [IHC (P)]
- Tested Dilution: 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | FOXP1, 44R |
| Immunogen | Recombinant fragment (around aa350–450) of human FOXP1 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Immunohistochemistry (PFA fixed):
Incubate antibody for 30 minutes at room temperature.
For formalin-fixed tissues, heat sections in 10 mM Tris with 1 mM EDTA (pH 9.0) for 45 minutes at 95°C, then cool at room temperature for 20 minutes.
Target Information
The FOXP1 gene belongs to subfamily P of the forkhead box (FOX) transcription factor family. These transcription factors regulate tissue- and cell type-specific gene expression during development and adulthood.
FOXP1 protein contains both DNA-binding and protein–protein interaction domains. This gene may act as a tumor suppressor, as it is lost in several tumor types and maps to chromosome region 3p14.1, which contains tumor suppressor gene(s).
Alternative splicing results in multiple transcript variants encoding different isoforms.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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