
Thermo Fisher Scientific CRLF1 Polyclonal Antibody
Human CRLF1 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P)에서 1:50–1:200 희석으로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며 PBS/glycerol buffer에 보존. 신경세포 생존 연구 등 CRLF1 관련 연구용으로 적합.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human CRLF1. Recombinant protein control fragment (Product # RP-98861) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2640164 |
Product Specific Information
Immunogen sequence:
HTAVISPQDP TLLIGSSLLA TCSVHGDPPG ATAEGLYWTL NGRRLPPELS RVLNASTLAL ALANLNGSRQ RSGDNLVCHA RDGSILAGSC LYVGLP
Highest antigen sequence identity to the following orthologs:
- Mouse: 93%
- Rat: 93%
Target Information
CRLF1 encodes a member of the cytokine type I receptor family. The protein forms a secreted complex with cardiotrophin-like cytokine factor 1 and acts on cells expressing ciliary neurotrophic factor receptors. This complex promotes survival of neuronal cells. Mutations in this gene are associated with Crisponi syndrome and cold-induced sweating syndrome.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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