Thermo Fisher Scientific SAPK4 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 0.2–1.0 µg/mL

Product Specifications

Product Specific Information

This target displays homology in the following species:
Cow: 100%; Dog: 93%; Goat: 93%; Guinea Pig: 93%; Horse: 77%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%; Yeast: 85%; Zebrafish: 86%

Target Information

MAPK13 (p38 delta) is a serine/threonine kinase that transduces a variety of extracellular signals, including cytokine and environmental stress responses. MAPK13 also regulates keratinocyte differentiation. This kinase is activated by various environmental stresses and proinflammatory cytokines. Activation requires phosphorylation by MAP kinase kinases or autophosphorylation triggered by interaction with MAP3K7IP1/TAB1. Substrates include ATF2, MEF2C, MAX, CDC25B, and p53, implicating roles in stress-related transcription, cell cycle regulation, and genotoxic stress response. Four alternatively spliced transcript variants of SAPK4 encoding distinct isoforms have been reported.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.