
Thermo Fisher Scientific SAPK4 Polyclonal Antibody
SAPK4 (p38 MAPK delta) 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot에 적합하며 Human 및 Mouse 반응성. 액상 형태, 0.5 mg/mL 농도, PBS + 2% sucrose buffer에 보관. 연구용 전용 제품.
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 0.2–1.0 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the middle region of human p38 MAPK delta |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2689425 |
Product Specific Information
This target displays homology in the following species:
Cow: 100%; Dog: 93%; Goat: 93%; Guinea Pig: 93%; Horse: 77%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%; Yeast: 85%; Zebrafish: 86%
Target Information
MAPK13 (p38 delta) is a serine/threonine kinase that transduces a variety of extracellular signals, including cytokine and environmental stress responses. MAPK13 also regulates keratinocyte differentiation. This kinase is activated by various environmental stresses and proinflammatory cytokines. Activation requires phosphorylation by MAP kinase kinases or autophosphorylation triggered by interaction with MAP3K7IP1/TAB1. Substrates include ATF2, MEF2C, MAX, CDC25B, and p53, implicating roles in stress-related transcription, cell cycle regulation, and genotoxic stress response. Four alternatively spliced transcript variants of SAPK4 encoding distinct isoforms have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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