Thermo Fisher Scientific RNF14 Monoclonal Antibody (OTI1C9)
RNF14 단백질을 인식하는 Thermo Fisher Scientific의 단클론 항체로, Western blot 및 IHC(P) 분석에 적합합니다. 인간 및 생쥐 시료에 반응하며, IgG2a 아이소타입입니다. 액상 형태로 제공되며, -20°C에서 보관합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1C9 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–220 of RNF14 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2725249 |
Target Information
The protein encoded by this gene contains a RING zinc finger, a motif known to be involved in protein–protein interactions. This protein interacts with the androgen receptor (AR) and may function as a coactivator that induces AR target gene expression in prostate tissue. A dominant negative mutant of this gene has been shown to inhibit AR-mediated growth of prostate cancer. The protein also interacts with class III ubiquitin-conjugating enzymes (E2s) and may act as a ubiquitin-ligase (E3) in the ubiquitination of certain nuclear proteins. Five alternatively spliced transcript variants encoding two distinct isoforms have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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