Thermo Fisher Scientific ARTS Polyclonal Antibody
인간 ARTS 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC(P) 및 ICC/IF에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS와 글리세롤 기반 용액으로 보관됩니다. 세포사멸 연구 및 TGF-β 신호전달 관련 연구에 유용합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human SEPT4. Recombinant protein control fragment (Product #RP-93188). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2789960 |
Product Specific Information
Immunogen sequence:
TMLVRTHMQD LKDVTRETHY ENYRAQCIQS MTRLVVKERN RNKLTRESGT DFPIPAVPPG TDPETEKLIR EKDEELRRMQ E
Target Information
Apoptosis is related to many diseases and development. Mitochondrial proteins such as cytochrome c, Apaf-1, and AIF play important roles in apoptosis.
A novel mitochondrial septin-like protein was identified recently and designated ARTS (apoptosis-related protein in TGF-beta signaling pathway).
ARTS, encoded by the human septin H5/PNUTL2/CDCrel2b gene, localizes to mitochondria and translocates to the nucleus during apoptosis.
It is expressed in many tissues and enhances cell death induced by TGF-beta and, to a lesser extent, by other apoptotic agents such as TNF-α and Fas ligand.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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