Thermo Fisher Scientific DHX36 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthesized peptide derived from human DHX36(Accession Q9H2U1), corresponding to amino acid residues I942-K992. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:DHX36,uniProtId:Q9H2U1-1,ncbiNodeId:9606,antigenRange:942-992,antigenLength:1008,antigenImageFileName:PA5-100473_DHX36_Q9H2U1-1_Rabbit.svg,antigenImageFileNamePDP:PA5-100473_DHX36_Q9H2U1-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_2849983

Product Specific Information

Antibody detects endogenous levels of total DHX36.

Target Information

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp, are putative RNA helicases implicated in several cellular processes involving modifications of RNA secondary structure. DHX36 (DEAH box protein 36), also known as MLE-like protein 1 and RNA helicase associated with AU-rich element ARE (RHAU), belongs to RNA helicase of the DEAH family and may function in sex development and spermatogenesis. It is expressed in testis and is evolutionary conserved with true orthologs in almost all animal species. DHX36 plays a role in degradation and deadenylation of mRNAs containing in their 3`-UTR the consensus ARE sequence element. DHX36 is required for early embryogenesis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.