Thermo Fisher Scientific PTPN23 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1230-1450 of human PTPN23 (NP_0562811) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:PTPN23,uniProtId:Q9H3S7-1,ncbiNodeId:9606,antigenRange:1230-1450,antigenLength:1636,antigenImageFileName:PA5-92262_PTPN23_Q9H3S7-1_Rabbit.svg,antigenImageFileNamePDP:PA5-92262_PTPN23_Q9H3S7-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.51 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2806424

Product Specific Information

Immunogen sequence: DSNRVVLRSG KDDYINASCV EGLSPYCPPL VATQAPLPGT AADFWLMVHE QKVSVIVMLV SEAEMEKQKV ARYFPTERGQ PMVHGALSLA LSSVRSTETH VERVLSLQFR DQSLKRSLVH LHFPTWPELG LPDSPSNLLR FIQEVHAHYL HQRPLHTPII VHCSSGVGRT GAFALLYAAV QEVEAGNGIP ELPQLVRRMR QQRKHMLQEK LHLRFCYEAV V; Positive Samples: Mouse eye, Rat kidney; Cellular Location: Cytoplasm, Cytoplasmic vesicle, Early endosome, Endosome, Nucleus, cilium basal body, cytoskeleton

Target Information

Plays a role in sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs) via its interaction with the ESCRT-I complex (endosomal sorting complex required for transport I), and possibly also other ESCRT complexes. May act as a negative regulator of Ras-mediated mitogenic activity. Plays a role in ciliogenesis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.