Thermo Fisher Scientific NRGN Monoclonal Antibody (OTI1A2), TrueMAB
인간 NRGN 단백질(1-78 aa)에 특이적인 Mouse IgG1 단클론 항체로, Western blot에 최적화됨. 액상 형태, 1 mg/mL 농도, PBS/BSA/glycerol buffer에 보관. 신경 특이 단백질 연구 및 신호전달 관련 연구용에 적합.
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Applications
- Western Blot (WB)
Tested Dilution: 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1A2 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–78 of human NRGN produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20 °C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Neurogranin (NRGN) is the human homolog of the neuron-specific rat RC3/neurogranin gene. It encodes a postsynaptic protein kinase substrate that binds calmodulin in the absence of calcium. The NRGN gene consists of four exons and three introns; exons 1 and 2 encode the protein, while exons 3 and 4 contain untranslated regions. NRGN is suggested to be a direct target for thyroid hormone in the human brain, and its expression regulation may underlie the effects of hypothyroidism on mental states during development and adulthood.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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