
Thermo Fisher Scientific NMD3 Polyclonal Antibody
NMD3 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 Immunoprecipitation에 적합합니다. Human과 Mouse 시료에 반응하며, 항원 친화 크로마토그래피로 정제되었습니다. 4°C에서 보관하며 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunoprecipitation (IP) | 2–10 µg/mg lysate |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 453 to 503 of human NMD3 Ribosome Export Adaptor |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Phosphate/Tris citrate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
NMD3 is a cytoplasmic factor required for a late cytoplasmic assembly step of the 60S ribosomal subunit but is not itself a ribosomal protein.
A mutation in NMD3 is lethal in the absence of XRN1, the major cytoplasmic exoribonuclease responsible for mRNA turnover.
Although the NMD3 protein sequence lacks recognizable motifs of known function, its orthologues contain an amino-terminal domain with four Cx2C repeats, reminiscent of zinc-binding proteins, suggesting roles in nucleic acid binding or protein oligomerization.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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