Thermo Fisher Scientific PCDHB7 Polyclonal Antibody
Rabbit polyclonal antibody against human PCDHB7. Validated for IHC, ICC/IF, and ELISA. Supplied as liquid, unconjugated form. Protein G purified, stored in PBS with 50% glycerol. Ideal for research on neural cell adhesion and protocadherin beta family.
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- PA5144372
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| ELISA | Assay-dependent |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human Protocadherin beta-7 protein (463–682 AA) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.61 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.03% Proclin 300 |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Wet ice |
| RRID | AB_3091440 |
Target Information
This gene is a member of the protocadherin beta gene cluster, one of three related clusters on chromosome 5. These clusters have a genomic organization similar to B-cell and T-cell receptor gene clusters. The beta cluster includes 16 genes and 3 pseudogenes, each encoding six extracellular cadherin domains and a unique cytoplasmic tail. The extracellular domains mediate homophilic interactions, contributing to specific cell-cell connections in neural tissue. Unlike the alpha and gamma clusters, beta cluster transcripts consist of a single large exon. These neural cadherin-like proteins are integral membrane proteins involved in neural connectivity, though their precise functions remain unclear. This family member uses multiple polyadenylation sites.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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