Thermo Fisher Scientific FLT3LG Monoclonal Antibody (4C4)
FLT3LG 단백질을 인식하는 Mouse IgG2a 단일클론 항체로, Western blot, ELISA, in situ PLA 등에 사용 가능. 인간 단백질 반응성으로 연구용 적합하며, PBS buffer에 보존되고 -20°C에서 보관. DC 발달 및 면역 반응 연구에 활용 가능.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| ELISA | 0.03 ng/mL |
| in situ PLA (PLA) | 1:1200 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 4C4 |
| Immunogen | FLT3LG (NP_001450, 27–136 a.a) partial recombinant protein with GST tag (MW of GST tag = 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
TQDCSFQHSP ISSDFAVKIR ELSDYLLQDY PVTVASNLQD EELCGGLWRL VLAQRWMERL KTVAGSKMQG LLERVNTEIH FVTKCAFQPP PSCLRFVQTN ISRLLQETSE
Target Information
FLT3LG (Fms Related Tyrosine Kinase 3 Ligand) is a protein-coding gene.
Diseases associated with FLT3LG include Aplastic Anemia and Brain Cancer.
Related pathways:
- Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers
- Ras signaling pathway
Gene Ontology (GO) annotations:
- Protein homodimerization activity
- Cytokine activity
Dendritic cells (DCs) link innate and adaptive immunity by recognizing pathogens and priming pathogen-specific immune responses. FLT3LG controls the development of DCs, particularly plasmacytoid DCs and CD8-positive classical DCs and their CD103-positive tissue counterparts.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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