Thermo Fisher Scientific Coilin Polyclonal Antibody
Thermo Fisher Scientific의 Coilin Polyclonal Antibody는 Rat에서 반응하며 Rabbit IgG로 제작된 비결합 액상 항체입니다. Western blot에 적합하며 Cajal bodies 연구에 활용됩니다. 고순도 친화 크로마토그래피 정제, 안정적 PBS/sucrose buffer 저장.
- 카탈로그번호
- PA569975
- 판매단위
- pk
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Thermo Fisher Scientific Coilin Polyclonal Antibody
Applications
- Western Blot (WB): 1.0 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the C-terminal region of rat Coilin |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2690361 |
Product Specific Information
This target displays homology in the following species:
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 91%
Target Information
The protein encoded by this gene is an integral component of Cajal bodies (also called coiled bodies).
Cajal bodies are nuclear suborganelles of varying number and composition that are involved in the post-transcriptional modification of small nuclear and small nucleolar RNAs.
The N-terminus of the coilin protein directs its self-oligomerization while the C-terminus influences the number of nuclear bodies assembled per cell.
Differential methylation and phosphorylation of coilin likely influence its localization among nuclear bodies and the composition and assembly of Cajal bodies.
This gene has pseudogenes on chromosome 4 and chromosome 14.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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