Thermo Fisher Scientific Thyroglobulin Polyclonal Antibody
Thyroglobulin 단백질을 검출하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot에 최적화되어 있으며 인간, 마우스, 랫트 반응성. Affinity chromatography로 정제된 액상 형태, 1 mg/mL 농도. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human TG (Accession P01266), corresponding to amino acid residues D2553–R2603 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2852316 |
Product Specific Information
Antibody detects endogenous levels of total Thyroglobulin.
Target Information
Human thyroglobulin (hTg) is a high molecular weight glycoprotein (605 kDa) found in thyroid follicular cells.
It plays a central role in the uptake, incorporation, and regulated biosynthesis of thyroid hormones T4 and T3.
Thyroid disorders are largely autoimmune in origin, and anti-thyroglobulin autoantibodies were the first discovered factor.
Anti-hTG is found in all thyroid autoimmune diseases (Hashimoto thyroiditis, Graves disease), with the highest levels observed in Hashimoto thyroiditis.
It is also characteristic of thyroid cancer and can be used for monitoring cancer patients.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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